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Dr. Abu Gafar Hossion

Instructor in Chemistry

Abu HossionEducational background

B.S. in Chemistry, Jahangirnagar University, Bangladesh, 2001
M.S. in Organic Chemistry, Jahangirnagar University, Bangladesh, 2002
M.S. in majoring Medicinal Chemistry, Okayama University, Japan, 2008
Ph.D. in majoring Medicinal Chemistry, Okayama University, Japan, 2011

Dr. Hossion has a diverse background in education, teaching and research from multiple institutions. He has several experiences in teaching undergraduate students, including a faculty position of Assistant Professor of Chemistry at Fort Hays State University, Chemistry Adjunct Faculty at Haskell Indian Nations University and others. He pursued postdoctoral studies in multidisciplinary research and in interdisciplinary teaching at College of Pharmacy of the University of Oklahoma Health Sciences Center, School of Medicine of the University of Pittsburgh and the University of Kansas, from July 2011 to July 2016. He came to Cloud County Community College in June 2016 and has much enthusiasm to explore the undergraduate chemistry education program.

In 2013, he was awarded the NIH IRACDA fellowship at the University of Kansas to develop undergraduate education and to assist the students from groups underrepresented. He had mentored and trained undergraduate research students at the University of Kansas and Fort Hays State University. In his postdoctoral studies in multidisciplinary research, he discovered a promising cancer treatment of photo-unclick chemistry of visible light controlled release of anticancer drug via singlet oxygen. He served as reviewer for several Journals including American Chemical Society Journal of Medicinal Chemistry, where was he recognized as an outstanding reviewer in  2013. He is the editor of the book of “Vancomycin: Biosynthesis, Clinical Uses and Adverse Effects”. He is serving as an editor of SF Journal of Pharmaceutical and analytical Chemistry.

 

Publications:

1.  Nagamatsu, T.; Ahmed, S.; Hossion, A. M. L.; and Ohno. S.; “Synthesis of Thieno[3.2-e][1,2,4]triazolo[1,5-c]pyrimidine-3(6H)-ones via their [1,2,4]triazolo[4,3-c]pyrimidine Compounds as New Ring Systems by Dimroth-Type Rearrangement” Heterocycles 2007, 73, 777. DOI: 10.1002/chin.200818153 

 2. Nagamatsu, T.; Ahmed, S.; Hossion, A. M. L.; Ohno, S. ChemInform Abstract: Synthesis of Thieno[3,2-e][1,2,4]triazolo[1,5-c]pyrimidin-5(6H)-ones via Their [1,2,4]Triazolo[4,3-c]pyrimidine Compounds as New Ring Systems by Dimroth-Type Rearrangement ChemInform 2008, 39 (18).

 3. Kandahary, R. K.; Hossion, A. M. L.; Ashida, N.; Nagamatsu, T.; “Novel and Facile Synthesis and Evaluation of Antitumor Activities of 6,7-bisaryl-1-(b-D-ribofurnosyl)pteridine-2,4-(1H,3H)-diones”, Heterocycles 2009, 80, 557.DOI: 10.1002/chin.201021199

 4. Hossion, A. M. L.; Islam, R.; Kandahary, R. K.; Nagamatsu, T.; Synthesis and Chemoselective N- and O- Alkylation of Thiadiazolopyridine Nuclosides and Uridines” Synthesis 2009, 16, 2689. DOI: 10.1055/s-0029-1216882

 5. Hossion, A. M. L.;* Otsuka, N.; Kandahary, R. K.; Tsuchiya, T.; Ogawa, W.; Iwado, A.; Zamami, Y.; Sasaki, K.; “Design, Synthesis and Biological Evaluation of a Novel Series of Quercetin Diacylglucosides as Potent Anti-MRSA and Anti-VRE Agents”. Bioorg. Med. Chem.  Lett. 2010, 20, 5349. http://dx.doi.org/10.1016/j.bmcl.2010.02.060

6. Rabbani, M. G.; Islam, M. R.; Ahmad, M.; Hossion, A. M. L. “Synthesis of some NH-Derivatives of Ciprofloxacin as Antibacterial and Antifungal Agents”. Bangladesh J. Pharmacol. 2011, 6, 8. DOI: http://dx.doi.org/10.3329/bjp.v6i1.7720

7. a) Hossion, A. M. L.;* Zamami, Y.; Kandahary, R. K.; Tsuchiya, T.; Ogawa, W.;    

Iwado, A.; Sasaki, K.; Quercetin Diacylglycoside Analogues Showing Dual Inhibition of DNA Gyrase and Topoisomerase IV as Novel Antibacterial Agents. J. Med. Chem. 2011. 54, 3686. dx.doi.org/10.1021/jm200010x

b) News Highlighted: Sasaki, K. and Hossion, A. M. L. “Bacterial infection; Gram-positive bacterial infection; EscherichiaStaphylococcusSciBX 4(22); doi: 10.1038/scibx.2011.629

8. Bio, M;  Rajaputra, P.; Nkepang, G.; Awuah, S. G.;  Hossion, A. M. L.and You, Y. Site-specific and Far-Red Light-Activatable Prodrug of Combretastain A-4 Using Photo-Unclick Chemistry. J.Med.Chem 2013, 56, 3936.http://pubs.acs.org/doi/abs/10.1021/jm400139w

9a) Hossion, A. M. L.; Moses, B.; Nkepang, G.; Awuah, S. and You, Y. Visible light controlled release of anticancer drug through double activation of prodrug. ACS Med. Chem. Lett. 2013, 4, 124.  http://pubs.acs.org/doi/abs/10.1021/ml3003617

b) Editorial choice:Hossion, et al. Turning on the Therapeutic by Light, ACS Med. Chem. Lett. 2013, 4, 1,  http://pubs.acs.org/doi/abs/10.1021/ml300442c

10. Hossion, A. M. L. and Sasaki, K. Novel Quercetin Glycosides as Potent Anti-

MRSA and Anti-VRE agents. Recent Pat Antiinfect Drug Discov. 2013, 8, 198. (Special issue 2014) http://www.ncbi.nlm.nih.gov/pubmed/24320230

 

Patents:

  1. Sasaki, K.; Tsuchiya, T.; Hossion, A. M. L. PCT Int. Pat. Appl. WO 2011013735. Novel flavanone derivatives. (National University Corporation Okayama University, Japan) http://www.google.com/patents/US20120202980?cl=ja

       2. You, Youngjae; Moses, Bio; Hossion, A. M. L. PCT Int. Pat. Appl. WO 2013163321 A1 “Singlet oxygen-labile linkers and methods of production and use thereof” (University of Oklahoma, Health Sciences Center) http://www.google.com/patents/WO2013163321A1?cl=en

Professional Societies:

1. American Chemical Society (ACS)

2. International Chemical Society of Heterocyclic Chemists (ISHC)

Contact
785-243-1435 ext 222
800-729-5101 ext 222

Email: Dr. Abu Hossion